SETD7/9 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18675

Novus Biologicals, part of Bio-Techne
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NBP3-18675-25ul
NBP3-18675-50ug
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

2 mg/ml

View all SETD7/9 Antibodies »

Product Summary for SETD7/9 Antibody

Immunogen

Polyclonal antibody raised in rabbit against human SETD7/9 (SET domain containing (lysine methyltransferase) 9), using a recombinant protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for SETD7/9 Antibody

Western Blot: SETD7/9 Antibody [NBP3-18675]

Western Blot: SETD7/9 Antibody [NBP3-18675]

Western Blot: SETD7/9 Antibody [NBP3-18675] - Figure 1. Western blot analysis using the antibody directed against SETD7/9 HeLa nuclear extracts (HeLa NE, 20 ug) were analysed by Western blot using the antibody against SETD7/9 diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. A molecular weight marker (in kDa) is shown on the left; the location of the protein of interest is indicated on the right.

Applications for SETD7/9 Antibody

Application
Recommended Usage

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide and 0.05% ProClin 300

Concentration

2 mg/ml

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.

Background: SETD7/9

Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly(ADP-ribosylation), ubiquitination and methylation. These modifications play critical roles in regulating chromatin structure and gene expression. Histone methyltransferases (HMTases) selectively methylate evolutionarily conserved arginine or lysine residues, primarily in the N-terminal tails of histones H3 and H4. Set7/9 is a histone specific HMTase that methylates histone H3 lysine 4. Set7/9 transfers methyl groups to lysine 4 of histone H3 in complex with S-adenosyl-L-methionine. Human Set7/9 is a 336 amino acid protein.

Alternate Names

EC 2.1.1.43, H3-K4-HMTase SETD7, histone H3-lysine 4-specific methyltransferase, histone-lysine N-methyltransferase SETD7, KIAA1717SET domain-containing protein 7, KMT7FLJ21193, Lysine N-methyltransferase 7, SET domain containing (lysine methyltransferase) 7, SET7/9Histone H3-K4 methyltransferase SETD7, SET7Set9, SET9

Gene Symbol

SETD7

UniProt

Q8WTS6 (Human)

Additional SETD7/9 Products

Product Documents for SETD7/9 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SETD7/9 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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