SH2D1A Antibody (S09-5F6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19771

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19771-100ul
NBP3-19771-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S09-5F6

Concentration

0.3 mg/ml

View all SH2D1A Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human SH2D1A (Uniprot # O60880)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

14 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SH2D1A Antibody (S09-5F6)

Western Blot: SH2D1A Antibody (S09-5F6) [NBP3-19771]

Western Blot: SH2D1A Antibody (S09-5F6) [NBP3-19771]

Western Blot: SH2D1A Antibody (S09-5F6) [NBP3-19771] - Western blot detection of SH2D1A in MCF7, C6 cell lysates using NBP3-19771 (1:1000 diluted). Predicted band size: 14KDa. Observed band size: 14KDa.

Applications for SH2D1A Antibody (S09-5F6)

Application
Recommended Usage

Western Blot

1/1000-1/2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SH2D1A

The cytoplasmic protein encoded by the SH2D1A gene plays an essential role in controlling EBV infection. It is expressed in T and NK cells, but not in B cells or in granulocytes. SH2D1A is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD)also known as Duncan disease. XLPD is characterized by an immunodeficiency following Epstein-Barr virus (EBV)infection. Symptoms include fatal mononucleosis, hypogammaglobulinemia, pancytopenia or malignant lymphoma.

Alternate Names

DSHP, EBVS, IMD5, LYP, MTCP1, XLP, XLPD

Gene Symbol

SH2D1A

Additional SH2D1A Products

Product Documents for SH2D1A Antibody (S09-5F6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SH2D1A Antibody (S09-5F6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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