SHANK1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87016

Novus Biologicals, part of Bio-Techne
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NBP1-87016
NBP1-87016-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SHANK1 Antibodies »

Product Summary for SHANK1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLP

Marker

TGN Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SHANK1 Antibody

Western Blot: SHANK1 Antibody [NBP1-87016]

Western Blot: SHANK1 Antibody [NBP1-87016]

Western Blot: SHANK1 Antibody [NBP1-87016] - Analysis in human cell line U-2 OS and human cell line RT-4.
Immunocytochemistry/ Immunofluorescence: SHANK1 Antibody [NBP1-87016]

Immunocytochemistry/ Immunofluorescence: SHANK1 Antibody [NBP1-87016]

Immunocytochemistry/Immunofluorescence: SHANK1 Antibody [NBP1-87016] - Staining of human cell line U-2 OS shows localization to plasma membrane.
Immunohistochemistry-Paraffin: SHANK1 Antibody [NBP1-87016]

Immunohistochemistry-Paraffin: SHANK1 Antibody [NBP1-87016]

Immunohistochemistry-Paraffin: SHANK1 Antibody [NBP1-87016] - Staining of human lateral ventricle shows strong positivity in glial cells.

Applications for SHANK1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200-1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SHANK1

Shank is a novel family of postsynaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.

Alternate Names

SH3 and multiple ankyrin repeat domains 1, SH3 and multiple ankyrin repeat domains protein 1, Shank1, Somatostatin receptor-interacting protein, SSTR-interacting protein, SSTRIPSPANK-1, synamon

Gene Symbol

SHANK1

Additional SHANK1 Products

Product Documents for SHANK1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SHANK1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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