CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages, although it is absent on granulocytes. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function. (1-4)

Long Name

Sialic Acid Binding Ig-like Lectin 3

Alternate Names

CD33, gp67, Siglec3

Gene Symbol

CD33

Additional Siglec-3/CD33 Products

Product Documents for Siglec-3/CD33 Antibody (CD33 3D6) [mFluor Violet 450 SE]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Siglec-3/CD33 Antibody (CD33 3D6) [mFluor Violet 450 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

Siglec-3/CD33 Antibody (CD33 3D6) [mFluor Violet 450 SE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-50291MFV450

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all Siglec-3/CD33 Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Applications for Siglec-3/CD33 Antibody (CD33 3D6) [mFluor Violet 450 SE]

ELISA

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: Siglec-3/CD33