Sin1/MAPKAP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56482

Novus Biologicals, part of Bio-Techne
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NB100-56482
NB100-56482SS
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Key Product Details

Species Reactivity

Human, Mouse, Rat, Avian, Bovine, Canine, Chicken, Zebrafish

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Sin1/MAPKAP1 Antibodies »

Product Specifications

Immunogen

A portion of amino acids 85-102 (NTAQRLERLRKERQNQIK) of human Mip1 was used as the immunogen.

Specificity

There are multiple isoforms of this protein, ranging from approximately 310 amino acids to approximately 522 amino acids. Isoform distribution varies with tissue type.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Sin1/MAPKAP1 Antibody

Western Blot: Sin1/MAPKAP1 Antibody [NB100-56482]

Western Blot: Sin1/MAPKAP1 Antibody [NB100-56482]

Western Blot: Sin1/MAPKAP1 Antibody [NB100-56482] - Analysis of Mip1 in human heart lysate in the 1) absence and 2) presence of immunizing peptide and in human skeletal muscle lysate in the 3) absence and 4) presence of immunizing peptide using this antibody. 5 ug/ml.

Applications for Sin1/MAPKAP1 Antibody

Application
Recommended Usage

Western Blot

0.5-2 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.2% gelatin

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Sin1/MAPKAP1

Mip1 is a novel member of a group of highly conserved proteins. Originally identified as a RAS suppressor protein, Mip1 is a human ortholog of S. cerevisiae Sin1. Studies reveal that Mip1 interacts with proteins involved in MAPK signaling including MEKK2 and participates in the regulation of MEKK2 activation and signaling. It also has been found to bind to JNK and might act as a scaffold molecule in the regulation of JNK signaling.

Long Name

Mitogen-Activated Protein Kinase Associated Protein 1

Alternate Names

JC310, MAPKAP1, MIP1

Entrez Gene IDs

79109 (Human); 227743 (Mouse); 296648 (Rat)

Gene Symbol

MAPKAP1

UniProt

Q92973 (Human)

Additional Sin1/MAPKAP1 Products

Product Documents for Sin1/MAPKAP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Sin1/MAPKAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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