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SLC45A3/Prostein Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89630

Novus Biologicals, part of Bio-Techne
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NBP1-89630
NBP1-89630-25ul

Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AEEAALGPTEPAEGLSAPSLSPHCCPCRARLAFRNLGALLPRLHQLCCRMP

Marker

Prostate Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SLC45A3/Prostein Antibody

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89630]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89630]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89630] - Staining in human prostate and liver tissues using NBP1-89630 antibody. Corresponding SLC45A3 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89630]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89630]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89630] - Staining of human liver, placenta, prostate and testis using Anti-SLC45A3 antibody NBP1-89630 (A) shows similar protein distribution across tissues to independent antibody NBP1-89629 (B).
Immunocytochemistry/ Immunofluorescence: SLC45A3/Prostein Antibody [NBP1-89630]

Immunocytochemistry/ Immunofluorescence: SLC45A3/Prostein Antibody [NBP1-89630]

Immunocytochemistry/Immunofluorescence: SLC45A3/Prostein Antibody [NBP1-89630] - Staining of human cell line A-431 shows localization to vesicles. Antibody staining is shown in green.

Applications for SLC45A3/Prostein Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

Reported in scientific literature (PMID: 30719129).
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC45A3/Prostein

Prostein is a novel prostate-specific protein expressed in normal and malignant prostate tissues. This protein appears to be a type IIIa plasma membrane protein with a cleavable signal peptide and 11 transmembrane-spanning regions. Prostein expression is androgen responsive since treatment of LNCaP cells with androgen up-regulates prostein message and protein expression levels. Thus, prostein is a prostate-specific marker whose detection and quantitation may be useful in diagnosing and monitoring prostate cancer.

Long Name

Solute Carrier Family 45 Member 3

Alternate Names

IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, Prostein, PRST, S45A3

Gene Symbol

SLC45A3

Additional SLC45A3/Prostein Products

Product Documents for SLC45A3/Prostein Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SLC45A3/Prostein Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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