SLC6A4/5-HTTLPR/Serotonin transporter Antibody (2A9)

Novus Biologicals, part of Bio-Techne | Catalog # H00006532-M06

Novus Biologicals, part of Bio-Techne
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H00006532-M06
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Rat

Applications

Validated:

ELISA, Immunoprecipitation

Cited:

Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2A9

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SLC6A4/5-HTTLPR Antibodies »

Product Specifications

Immunogen

SLC6A4 (NP_001036, 181 a.a. ~ 252 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. AWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGIS

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 22451649).

Specificity

SLC6A4 (2A9)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (2A9)

ELISA: SLC6A4/5-HTTLPR/Serotonin transporter Antibody (2A9) [H00006532-M06]

ELISA: SLC6A4/5-HTTLPR/Serotonin transporter Antibody (2A9) [H00006532-M06]

ELISA: SLC6A4/5-HTTLPR/Serotonin transporter Antibody (2A9) [H00006532-M06] - Detection limit for recombinant GST tagged SLC6A4 is approximately 0.3ng/ml as a capture antibody.

Applications for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (2A9)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against recombinant protein on ELISA. GST alone used as a negative control. IP usage was reported in scientific literature.

Reviewed Applications

Read 1 review rated 4 using H00006532-M06 in the following applications:

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SLC6A4/5-HTTLPR

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Long Name

Solute Carrier Family 6 Member 4

Alternate Names

5-HT Transporter, 5-HTT, 5-HTTLPR, 5HTTLPR, OCD1, Serotonin Transporter 1, SERT

Entrez Gene IDs

6532 (Human)

Gene Symbol

SLC6A4

OMIM

164230 (Human)

UniProt

NP_001036

Additional SLC6A4/5-HTTLPR Products

Product Documents for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (2A9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (2A9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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