SLC6A4/5-HTTLPR/Serotonin transporter Antibody (SR2165)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21914

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21914-100ul
NBP3-21914-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2165

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SLC6A4/5-HTTLPR Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human SLC6A4/5-HTTLPR/Serotonin transporter (Uniprot #: P31645)

Specificity

Detects endogenous levels of total SLC6A4/5-HTTLPR/Serotonin transporter

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (SR2165)

Western Blot: SLC6A4/5-HTTLPR/Serotonin transporter Antibody (SR2165) [NBP3-21914] -

Western Blot: SLC6A4/5-HTTLPR/Serotonin transporter Antibody (SR2165) [NBP3-21914] - Western blot analysis using NBP3-21914 in Human fetal liver lysate.

Applications for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (SR2165)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC6A4/5-HTTLPR

Serotonin transporter encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Long Name

Solute Carrier Family 6 Member 4

Alternate Names

5-HT Transporter, 5-HTT, 5-HTTLPR, 5HTTLPR, OCD1, Serotonin Transporter 1, SERT

Gene Symbol

SLC6A4

Additional SLC6A4/5-HTTLPR Products

Product Documents for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (SR2165)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (SR2165)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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