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Smallpox B5R Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56453

Novus Biologicals, part of Bio-Techne
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NB100-56453
NB100-56453SS

Key Product Details

Species Reactivity

Virus

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Amino acids 200-214 (GSDVDKKDTHGNTPF) of the B5R protein were used as the immunogen.

Reactivity Notes

Reacts with Variola virus.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Smallpox B5R Antibody

Western Blot: Smallpox B5R Antibody [NB100-56453]

Western Blot: Smallpox B5R Antibody [NB100-56453]

Western Blot: Smallpox B5R Antibody [NB100-56453] - analysis of B5R in (A) recombinant fusion protein containing amino acids 200-214 and (B) fusion partner without these amino acids, using this antibody. 0.1 ug/ml.

Applications for Smallpox B5R Antibody

Application
Recommended Usage

Western Blot

0.1-1 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.2% gelatin

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Smallpox B5R

Vaccinia virus, a member of Poxviridae family, is a dsDNA enveloped virus. It consists of 4 types of virion stages among which extracellular enveloped virus (EEV) is critical for cell-to-cell and long range viral infection. B5R is an EEV-specific Type I membrane glycoprotein essential for EEV formation. It consists of a large ectodomain containing regions similar to SCR domains of complement regulatory proteins followed by a transmembrane region and a cytoplasmic tail. B5R is essential for efficient wrapping of IMV, actin tail formation, normal plaque size, virus virulence, incorporation of the protein into EEV and for EEV formation.

Alternate Names

B5R protein, B6R, B7R, B7R protein, EEV membrane glycoprotein, Glycoprotein, H7R, H7R protein, ORF5R, VARVgp175

Gene Symbol

B7R

Additional Smallpox B5R Products

Product Documents for Smallpox B5R Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Smallpox B5R Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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