SMG7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88486

Novus Biologicals, part of Bio-Techne
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NBP1-88486
NBP1-88486-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SMG7 Antibodies »

Product Summary for SMG7 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SMG7 Antibody

Immunocytochemistry/ Immunofluorescence: SMG7 Antibody [NBP1-88486]

Immunocytochemistry/ Immunofluorescence: SMG7 Antibody [NBP1-88486]

Immunocytochemistry/Immunofluorescence: SMG7 Antibody [NBP1-88486] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: SMG7 Antibody [NBP1-88486]

Immunohistochemistry-Paraffin: SMG7 Antibody [NBP1-88486]

Immunohistochemistry-Paraffin: SMG7 Antibody [NBP1-88486] - Staining of human esophagus shows strong cytoplasmic positivity in squamous epithelial cells.

Applications for SMG7 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SMG7

SMG7 plays a role in the dephosphorylation of UPF1, an RNA-dependent ATPase and helicase critical to nonsense-mediated mRNA decay (NMD). It is a homolog of the C. elegans NMD factor Smg7 (suppressor with morphogenetic effect on genitalia protein 7). SMG7 functions as an adaptor to target protein phosphatase 2A to UPF1 for dephosphorylation of UPF1.

Alternate Names

breast cancer-associated antigen SGA-56M, C1orf16, chromosome 1 open reading frame 16, EST1 telomerase component homolog C, EST1CKIAA0250SGA56M, EST1-like protein C, ever shorter telomeres 1C, FLJ23717, hSMG-7, protein SMG7, SMG-7, SMG-7 homolog, Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)

Gene Symbol

SMG7

Additional SMG7 Products

Product Documents for SMG7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SMG7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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