SNW1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77304

Novus Biologicals, part of Bio-Techne
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NBP1-77304
NBP1-77304-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all SNW1 Antibodies »

Product Summary for SNW1 Antibody - BSA Free

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human SkiP. The immunogen is located within the last 50 amino acids of SkiP. Amino Acid Squence: SRPKEHEHEGKKRRKE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SNW1 Antibody - BSA Free

Western Blot: SNW1 AntibodyBSA Free [NBP1-77304]

Western Blot: SNW1 AntibodyBSA Free [NBP1-77304]

Western Blot: SNW1 Antibody [NBP1-77304] - Analysis of SkiP in mouse skeletal muscle tissue lysate with SkiP antibody at 0.5 ug/ml.
Immunohistochemistry: SNW1 Antibody - BSA Free [NBP1-77304]

Immunohistochemistry: SNW1 Antibody - BSA Free [NBP1-77304]

Immunohistochemistry: SNW1 Antibody [NBP1-77304] - Immunofluorescence of Ski in human kidney tissue with Ski antibody at 20 ug/mL.

Applications for SNW1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

20 ug/ml

Western Blot

0.5 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SNW1

TGF-beta and the bone morphogenic proteins (BMPs) are key signaling proteins that regulate numerous cellular processes such as embryonic development and tumorigenesis. Both signal through the Smad protein family and are negatively regulated by Ski and SnoN, two related proto-oncoproteins. Ski functions by binding to the Smad proteins activated by TGF-beta and the (BMPs) and preventing their phosphorylation, inhibiting their ability to bind DNA and activate the transcription of downstream genes. SkiP was originally identified as a Ski-interacting protein and was later found to augment the signals induced by TGF-beta but inhibit transcription induced by BMP-2 in C2C12 cells, suggesting that SkiP is a key player in the signaling cascades inititated by TGF-beta and the BMP protein family.

Alternate Names

Bx42, homolog of Drosophila BX42, MGC119379, NCOA-62, Nuclear protein SkiP, Nuclear receptor coactivator NCoA-62, nuclear receptor coactivator, 62-kD, Prp45, PRPF45, SKI interacting protein, Ski-interacting protein, SKIPSKIIP, SNW domain containing 1, SNW domain-containing protein 1

Gene Symbol

SNW1

UniProt

NP_036377 (Human)

Additional SNW1 Products

Product Documents for SNW1 Antibody - BSA Free

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Product Specific Notices for SNW1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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