SNX2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89485

Novus Biologicals, part of Bio-Techne
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NBP1-89485
NBP1-89485-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SNX2 Antibodies »

Product Summary for SNX2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SNX2 Antibody

Western Blot: SNX2 Antibody [NBP1-89485]

Western Blot: SNX2 Antibody [NBP1-89485]

Western Blot: SNX2 Antibody [NBP1-89485] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue
Immunocytochemistry/ Immunofluorescence: SNX2 Antibody [NBP1-89485]

Immunocytochemistry/ Immunofluorescence: SNX2 Antibody [NBP1-89485]

Immunocytochemistry/Immunofluorescence: SNX2 Antibody [NBP1-89485] - Staining of human cell line A-431 shows localization to endosomes & lysosomes.
Immunohistochemistry-Paraffin: SNX2 Antibody [NBP1-89485]

Immunohistochemistry-Paraffin: SNX2 Antibody [NBP1-89485]

Immunohistochemistry-Paraffin: SNX2 Antibody [NBP1-89485] - Staining of human kidney shows strong cytoplasmic and extracellular positivity in tubule cells.
View 1 more images

Applications for SNX2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SNX2

SNX2 (Sorting nexin 2) is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. SNX2 is a component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. It may form oligomeric complexes with family members.

Alternate Names

MGC5204, sorting nexin 2, sorting nexin-2, Transformation-related gene 9 protein, TRG-9

Gene Symbol

SNX2

Additional SNX2 Products

Product Documents for SNX2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SNX2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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