SNX2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21431

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SNX2 Antibodies »

Product Summary for SNX2 Antibody

Immunogen

Produced in rabbits immunized with E. coli-derived Human SNX2 fragment

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C.

Scientific Data Images for SNX2 Antibody

SNX2 Antibody Immunocytochemistry/Immunofluorescence: SNX2 Antibody [NBP3-21431]

Immunocytochemistry/Immunofluorescence: SNX2 Antibody [NBP3-21431]

Immunofluorescence staining of SNX2 in A431 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with NBP3-21431 (dilution ratio 1:100) at 4C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
SNX2 Antibody Immunohistochemistry-Paraffin: SNX2 Antibody [NBP3-21431]

Immunohistochemistry-Paraffin: SNX2 Antibody [NBP3-21431]

Immunochemical staining of SNX2 in human kidney formalin-fixed paraffin embedded sections with NBP3-21431 at 1:100 dilution
SNX2 Antibody Immunohistochemistry-Paraffin: SNX2 Antibody [NBP3-21431]

Immunohistochemistry-Paraffin: SNX2 Antibody [NBP3-21431]

Immunochemical staining of SNX2 in human lymph node formalin-fixed paraffin embedded sections with NBP3-21431 at 1:100 dilution
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Applications for SNX2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry-Paraffin

1:50-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS, pH 7.0

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SNX2

SNX2 (Sorting nexin 2) is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. SNX2 is a component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. It may form oligomeric complexes with family members.

Alternate Names

MGC5204, sorting nexin 2, sorting nexin-2, Transformation-related gene 9 protein, TRG-9

Gene Symbol

SNX2

Additional SNX2 Products

Product Documents for SNX2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SNX2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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