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SOCS-4 Antibody (2G8)

Novus Biologicals, part of Bio-Techne | Catalog # H00122809-M01

Novus Biologicals, part of Bio-Techne
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H00122809-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 2G8

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

SOCS4 (AAH60790, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEVSLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKRKIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRNMEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTSSRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQC

Reactivity Notes

Human. Other species not tested.

Specificity

SOCS4 (2G8)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for SOCS-4 Antibody (2G8)

Western Blot: SOCS-4 Antibody (2G8) [H00122809-M01]

Western Blot: SOCS-4 Antibody (2G8) [H00122809-M01]

Western Blot: SOCS-4 Antibody (2G8) [H00122809-M01] - Analysis of SOCS4 expression in transfected 293T cell line by SOCS4 monoclonal antibody (M01), clone 2G8.Lane 1: SOCS4 transfected lysate(50.6 KDa).Lane 2: Non-transfected lysate.
Sandwich ELISA: SOCS-4 Antibody (2G8) [H00122809-M01] - Detection limit for recombinant GST tagged SOCS4 is 0.3 ng/ml as a capture antibody.

Applications for SOCS-4 Antibody (2G8)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against transfected lysate and recombinant protein for western blot. It has also been used for ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SOCS-4

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Long Name

Suppressor Of Cytokine Signaling 4

Alternate Names

CIS4, SOCS-7, SOCS4, SSI4

Entrez Gene IDs

122809 (Human)

Gene Symbol

SOCS4

Additional SOCS-4 Products

Product Documents for SOCS-4 Antibody (2G8)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SOCS-4 Antibody (2G8)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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