SOD1/Cu-Zn SOD Antibody (S08-5A5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20005

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-20005-100ul
NBP3-20005-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-5A5

Concentration

0.3 mg/ml

View all SOD1/Cu-Zn SOD Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human SOD1/Cu-Zn SOD (Uniprot # P00441)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

18 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SOD1/Cu-Zn SOD Antibody (S08-5A5)

Immunohistochemistry-Paraffin: SOD1/Cu-Zn SOD Antibody (S08-5A5) [NBP3-20005]

Immunohistochemistry-Paraffin: SOD1/Cu-Zn SOD Antibody (S08-5A5) [NBP3-20005]

Immunohistochemistry-Paraffin: SOD1/Cu-Zn SOD Antibody (S08-5A5) [NBP3-20005] - Immunohistochemical of SOD1/Cu-Zn SOD in Human breast cancer tissue using NBP3-20005 at dilution 1/50
SOD1/Cu-Zn SOD Antibody (S08-5A5)

Western Blot: SOD1/Cu-Zn SOD Antibody (S08-5A5) [NBP3-20005] -

Western Blot: SOD1/Cu-Zn SOD Antibody (S08-5A5) [NBP3-20005] - Western blot detection of A549, HL-60, C6 using NBP3-20005(1:1000 diluted)

Applications for SOD1/Cu-Zn SOD Antibody (S08-5A5)

Application
Recommended Usage

Flow Cytometry

1:20-1:100

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:1000-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

10mM PBS (pH 7.4), 150mM sodium chloride, 0.05% BSA, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SOD1/Cu-Zn SOD

FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. CATALYTIC ACTIVITY: 2 superoxide + 2 H+ = O2 + H2O2. COFACTOR: Binds 1 copper ion per subunit. COFACTOR: Binds 1 zinc ion per subunit. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. DISEASE: Defects in SOD1 are the cause of familial amyotrophic lateral sclerosis (FALS); also called amyotrophic lateral sclerosis 1 (ALS1 or ALS). ALS is a degenerative disorder of motorneurons in the cortex, brainstem and spinal cord. ALS is characterized by muscular weakness and atrophy beginning in the hands and spreading to the forearms and legs. Muscle fasciculations are commonly visible. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. ALS is sometimes referred to as Lou Gehrig disease after the famous American baseball player who was diagnosed with the disorder. FALS, the familial form of ALS, accounts for about 10% of the cases and is transmitted in an autosomal dominant manner. The mean age at onset of FALS is 45 years. MISCELLANEOUS: Zinc binding promotes dimerization. SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.

Long Name

Superoxide Dismutase-1

Alternate Names

Cu-Zn SOD, CuZn SOD, Ipo1, IPOA, SOD, cytosolic, SOD, Soluble

Gene Symbol

SOD1

Additional SOD1/Cu-Zn SOD Products

Product Documents for SOD1/Cu-Zn SOD Antibody (S08-5A5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SOD1/Cu-Zn SOD Antibody (S08-5A5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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