Sodium Potassium ATPase Alpha 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-10276

Novus Biologicals, part of Bio-Techne
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NBP3-10276-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

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Product Summary for Sodium Potassium ATPase Alpha 2 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human Sodium Potassium ATPase Alpha 2 (NP_000693.1). Peptide sequence TTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGV

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

112 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Sodium Potassium ATPase Alpha 2 Antibody

Western Blot: Sodium Potassium ATPase Alpha 2 Antibody [NBP3-10276]

Western Blot: Sodium Potassium ATPase Alpha 2 Antibody [NBP3-10276]

Western Blot: Sodium Potassium ATPase Alpha 2 Antibody [NBP3-10276] - Western blot analysis of Sodium Potassium ATPase Alpha 2 in Human Du145 Whole Cell lysates. Antibody dilution at 1ug/ml

Applications for Sodium Potassium ATPase Alpha 2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Sodium Potassium ATPase Alpha 2

The ubiquitously expressed sodium/potassium-ATPase exists as a oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motifs, sodium/potassium-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, alpha, beta and gamma, comprise to form the sodium/potassium-ATPase oligomer. The 113 kDa alpha subunit contains the binding sites for ATP and the cations. With a molecular weight between 40 and 60 kDa, the glycosylated beta subunit ensures correct folding and membrane insertion of the alpha subunits. The small 6 kDa gamma subunit co-localizes with the alpha subunit in nephron segments, where it increases the affinity of sodium/potassium-ATPase for ATP. The beta subunit, but not the gamma subunit, is essential for normal activity of sodium/potassium-ATPase.

Long Name

Sodium/potassium-transporting ATPase subunit alpha-2

Alternate Names

ATP1A2, KIAA0778

Gene Symbol

ATP1A2

Additional Sodium Potassium ATPase Alpha 2 Products

Product Documents for Sodium Potassium ATPase Alpha 2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Sodium Potassium ATPase Alpha 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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