Somatostatin R3/SSTR3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12903

Novus Biologicals, part of Bio-Techne
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NBP3-12903
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Somatostatin R3/SSTR3 Antibodies »

Product Specifications

Immunogen

Recombinant protein corresponding to human Somatostatin R3/SSTR3.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for Somatostatin R3/SSTR3 Antibody

Western Blot: Somatostatin R3/SSTR3 Antibody [NBP3-12903]

Western Blot: Somatostatin R3/SSTR3 Antibody [NBP3-12903]

Western Blot: Somatostatin R3/SSTR3 Antibody [NBP3-12903] - Various tissue extracts (50 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Somatostatin R3/SSTR3 antibody (NBP3-12903) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunocytochemistry/ Immunofluorescence: Somatostatin R3/SSTR3 Antibody [NBP3-12903]

Immunocytochemistry/ Immunofluorescence: Somatostatin R3/SSTR3 Antibody [NBP3-12903]

Immunocytochemistry/Immunofluorescence: Somatostatin R3/SSTR3 Antibody [NBP3-12903] - Somatostatin R3/SSTR3 antibody detects Somatostatin R3/SSTR3 protein by immunofluorescent analysis. Sample: DIV10 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Somatostatin R3/SSTR3 stained by Somatostatin R3/SSTR3 antibody (NBP3-12903) diluted at 1:500. Red: alpha Tubulin, stained by alpha Tubulin antibody [GT114] (NBP2-43837) diluted at 1:500. Blue: Fluoroshield with DAPI.
Immunohistochemistry-Paraffin: Somatostatin R3/SSTR3 Antibody [NBP3-12903]

Immunohistochemistry-Paraffin: Somatostatin R3/SSTR3 Antibody [NBP3-12903]

Immunohistochemistry-Paraffin: Somatostatin R3/SSTR3 Antibody [NBP3-12903] - Somatostatin R3/SSTR3 antibody detects Somatostatin R3/SSTR3 protein at cell membrane and cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. Somatostatin R3/SSTR3 stained by Somatostatin R3/SSTR3 antibody (NBP3-12903) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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Applications for Somatostatin R3/SSTR3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Somatostatin R3/SSTR3

Expression of Somatostatin Receptor Type 3 (SSTR3) has been reported in brain, breast, eye, gastrointestinal tract, pancreas, and thyroid. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This "turn-off" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Long Name

Somatostatin Receptor Type 3

Alternate Names

SomatostatinR3, SSR-28, SST3, SSTR3

Gene Symbol

SSTR3

Additional Somatostatin R3/SSTR3 Products

Product Documents for Somatostatin R3/SSTR3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Somatostatin R3/SSTR3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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