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SOX4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89506

Novus Biologicals, part of Bio-Techne
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NBP1-89506
NBP1-89506-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SOX4 Antibody

Immunocytochemistry/ Immunofluorescence: SOX4 Antibody [NBP1-89506]

Immunocytochemistry/ Immunofluorescence: SOX4 Antibody [NBP1-89506]

Immunocytochemistry/Immunofluorescence: SOX4 Antibody [NBP1-89506] - Staining of human cell line U-251 MG shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: SOX4 Antibody [NBP1-89506]

Immunohistochemistry-Paraffin: SOX4 Antibody [NBP1-89506]

Immunohistochemistry-Paraffin: SOX4 Antibody [NBP1-89506] - Staining of human pancreas shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: SOX4 Antibody [NBP1-89506]

Immunohistochemistry-Paraffin: SOX4 Antibody [NBP1-89506]

Immunohistochemistry-Paraffin: SOX4 Antibody [NBP1-89506] - Staining of human testis shows moderate nuclear positivity in cells in seminiferous ducts.

Applications for SOX4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SOX4

SOX4 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.

Alternate Names

ecotropic viral integration site 16, EVI16, SRY (sex determining region Y)-box 4, SRY-related HMG-box gene 4, transcription factor SOX-4

Gene Symbol

SOX4

Additional SOX4 Products

Product Documents for SOX4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SOX4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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