SPG11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-82143

Novus Biologicals, part of Bio-Techne
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NBP1-82143
NBP1-82143-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SPG11 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: IKFPWKLTDAIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRIDSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVKGQLLKICFYTT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SPG11 Antibody

Immunocytochemistry/ Immunofluorescence: SPG11 Antibody [NBP1-82143]

Immunocytochemistry/ Immunofluorescence: SPG11 Antibody [NBP1-82143]

Immunocytochemistry/Immunofluorescence: SPG11 Antibody [NBP1-82143] - Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.
Immunohistochemistry-Paraffin: SPG11 Antibody [NBP1-82143]

Immunohistochemistry-Paraffin: SPG11 Antibody [NBP1-82143]

Immunohistochemistry-Paraffin: SPG11 Antibody [NBP1-82143] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Applications for SPG11 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SPG11

SPG11 is encoded by this gene is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

Colorectal carcinoma-associated protein, FLJ21439spatacsin, KIAA1840DKFZp762B1512, spastic paraplegia 11 (autosomal recessive), Spastic paraplegia 11 protein

Gene Symbol

SPG11

Additional SPG11 Products

Product Documents for SPG11 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SPG11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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