SPG3A Antibody (1B9)

Novus Biologicals, part of Bio-Techne | Catalog # H00051062-M03

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1B9

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SPG3A Antibodies »

Product Specifications

Immunogen

SPG3A (NP_056999, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWV

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 31396305).

Specificity

SPG3A - spastic paraplegia 3A (autosomal dominant)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for SPG3A Antibody (1B9)

Western Blot: SPG3A Antibody (1B9) [H00051062-M03]

Western Blot: SPG3A Antibody (1B9) [H00051062-M03]

Western Blot: SPG3A Antibody (1B9) [H00051062-M03] - Analysis of SPG3A expression in PC-12 (Cat # L012V1).
Western Blot: SPG3A Antibody (1B9) [H00051062-M03]

Western Blot: SPG3A Antibody (1B9) [H00051062-M03]

Western Blot: SPG3A Antibody (1B9) [H00051062-M03] - Analysis of SPG3A expression in IMR-32 (Cat # L008V1).
ELISA: SPG3A Antibody (1B9) [H00051062-M03]

ELISA: SPG3A Antibody (1B9) [H00051062-M03]

ELISA: SPG3A Antibody (1B9) [H00051062-M03] - Detection limit for recombinant GST tagged SPG3A is approximately 1ng/ml as a capture antibody.

Applications for SPG3A Antibody (1B9)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA. Use in Immunohistochemistry-paraffin reported in scientific literature (PMID:31396305).

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SPG3A

The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

Long Name

Atlastin-1

Alternate Names

ATL1, GBP-3, GBP3, hGBP3

Entrez Gene IDs

51062 (Human)

Gene Symbol

ATL1

OMIM

182600 (Human)

UniProt

NP_056999 (Human)

Additional SPG3A Products

Product Documents for SPG3A Antibody (1B9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SPG3A Antibody (1B9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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