SPG3A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12986

Novus Biologicals, part of Bio-Techne
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NBP3-12986
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (98%), Rat (98%), Rhesus Macaque (99%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SPG3A Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human SPG3A. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for SPG3A Antibody

Immunocytochemistry/ Immunofluorescence: SPG3A Antibody [NBP3-12986]

Immunocytochemistry/ Immunofluorescence: SPG3A Antibody [NBP3-12986]

Immunocytochemistry/Immunofluorescence: SPG3A Antibody [NBP3-12986] - SPG3A antibody detects SPG3A protein at cytoplasm by immunofluorescent analysis. Sample: SK-N-SH cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: SPG3A protein stained by SPG3A antibody (NBP3-12986) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um.

Applications for SPG3A Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SPG3A

SPG3A is encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

Long Name

Atlastin-1

Alternate Names

ATL1, GBP-3, GBP3, hGBP3

Gene Symbol

ATL1

Additional SPG3A Products

Product Documents for SPG3A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SPG3A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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