SRD5A2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-36990

Novus Biologicals, part of Bio-Techne
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NBP1-36990
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all SRD5A2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KMFEDYPKSRK corresponding to C-Terminus according to NP_000339.2.

Epitope

C Terminus

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for SRD5A2 Antibody

Western Blot: SRD5A2 Antibody [NBP1-36990]

Western Blot: SRD5A2 Antibody [NBP1-36990]

Western Blot: SRD5A2 Antibody [NBP1-36990] - (1ug/ml) Analysis of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for SRD5A2 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 29 kDa band observed in human testis lysates (calculated MW of 28.4 kDa band according to NP_000339.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SRD5A2

This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).

Long Name

3-oxo-5-alpha-steroid 4-dehydrogenase 2

Alternate Names

5 alpha-SR2, S5AR 2, SR type 2

Entrez Gene IDs

6716 (Human); 64677 (Rat)

Gene Symbol

SRD5A2

UniProt

NP_000339.2 (Human)

Additional SRD5A2 Products

Product Documents for SRD5A2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SRD5A2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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