SSRP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18676

Novus Biologicals, part of Bio-Techne
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NBP3-18676-25ul
NBP3-18676-50ug
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

2 mg/ml

View all SSRP1 Antibodies »

Product Summary for SSRP1 Antibody

Immunogen

Polyclonal antibody raised in rabbit against human SSRP1 (Structure-specific recognition protein 1), the GST tagged N-terminal part of the protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for SSRP1 Antibody

Western Blot: SSRP1 Antibody [NBP3-18676]

Western Blot: SSRP1 Antibody [NBP3-18676]

Western Blot: SSRP1 Antibody [NBP3-18676] - Figure 1. Western blot analysis using the antibody directed against hSSRP1 Western blot was performed on nuclear extracts from HeLa cells (20 ug) using the antibody against hSSRP1 diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. A molecular weight marker (in kDa) is shown on the left. The location of the protein of interest is indicated by an arrow.

Applications for SSRP1 Antibody

Application
Recommended Usage

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide and 0.05% ProClin 300

Concentration

2 mg/ml

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.

Background: SSRP1

SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT complex is composed of the SUPT16H (FACT140) and the SSRP1 FACTp80 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. This protein interacts with dsDNA. The SSRP1 protein has been shown to be modified by cisplatin and may protect DNA from repair and block DNA replication. The 10D7 monoclonal antibody recognizes the human SSRP1 protein and has been shown to be useful for Western blotting.

Alternate Names

Chromatin-specific transcription elongation factor 80 kDa subunit, cisplatin-DNA SSRP, facilitates chromatin remodeling 80 kDa subunit, Facilitates chromatin transcription complex 80 kDa subunit, Facilitates chromatin transcription complex subunit SSRP1, FACT, FACT complex subunit SSRP1, FACT80FACT 80 kDa subunit, FACTp80, high mobility group box, hSSRP1, Recombination signal sequence recognition protein 1, structure specific recognition protein 1, Structure-specific recognition protein 1, T160

Gene Symbol

SSRP1

UniProt

Q08945 (Human)

Additional SSRP1 Products

Product Documents for SSRP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SSRP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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