STAG2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-30473

Novus Biologicals, part of Bio-Techne
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NBP1-30473
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all STAG2 Antibodies »

Product Summary for STAG2 Antibody

Immunogen

The immunogen for this product maps to a region between residue 1125 and 1175 of human stromal antigen 2 using the numbering given in entry NP_006594.3 (GeneID 10735).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for STAG2 Antibody

Western Blot: STAG2 Antibody [NBP1-30473]

Western Blot: STAG2 Antibody [NBP1-30473]

Western Blot: STAG2 Antibody [NBP1-30473] - Whole cell lysate from HeLa and 293T cells. SA2 was also immunoprecipitated by rabbit anti-SA2 antibody NBP1-30472.
Immunohistochemistry: STAG2 Antibody [NBP1-30473]

Immunohistochemistry: STAG2 Antibody [NBP1-30473]

Immunohistochemistry: STAG2 Antibody [NBP1-30473] - Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti- SA2 used at a dilution of 1:1,000 (0.2ug/ml). Detection: DAB

Applications for STAG2 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: STAG2

SA2 is a component of the cohesin complex, which is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which, sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. The subunit interacts directly with RAD21 in cohesin complex. Cohesin complexes are composed of a heterodimer between a SMC1 protein (SMC1L1 or SMC1L2) and SMC3, which are attached via their hinge domain, and RAD21 links them at their heads, and one STAG protein (STAG1, STAG2 or STAG3). In cohesin complexes, STAG2 is mutually exclusive with STAG1 and STAG3.

Alternate Names

bA517O1.1, cohesin subunit SA-2, DKFZp686P168, SA-2, SA2FLJ25871, SCC3 homolog 2, stromal antigen 2DKFZp781H1753

Gene Symbol

STAG2

Additional STAG2 Products

Product Documents for STAG2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for STAG2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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