Stanniocalcin 2/STC-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-92447

Novus Biologicals, part of Bio-Techne
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NBP1-92447
NBP1-92447-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Stanniocalcin 2/STC-2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SAIQKPPTAPPERQPQVDRTKLSRAHHGEAGHHLPEPSSRETGRGAKGERGSKSHPNAHARGRVGGLGAQGPSGSSEWEDEQSEYSDIRR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Stanniocalcin 2/STC-2 Antibody

Western Blot: Stanniocalcin 2/STC-2 Antibody [NBP1-92447]

Western Blot: Stanniocalcin 2/STC-2 Antibody [NBP1-92447]

Western Blot: Stanniocalcin 2/STC-2 Antibody [NBP1-92447] - Analysis in human cell line TD47D.
Immunocytochemistry/ Immunofluorescence: Stanniocalcin 2/STC-2 Antibody [NBP1-92447]

Immunocytochemistry/ Immunofluorescence: Stanniocalcin 2/STC-2 Antibody [NBP1-92447]

Immunocytochemistry/Immunofluorescence: Stanniocalcin 2/STC-2 Antibody [NBP1-92447] - Immunofluorescent staining of human cell line U-251 MG shows localization to endoplasmic reticulum.
Immunohistochemistry-Paraffin: Stanniocalcin 2/STC-2 Antibody [NBP1-92447]

Immunohistochemistry-Paraffin: Stanniocalcin 2/STC-2 Antibody [NBP1-92447]

Immunohistochemistry-Paraffin: Stanniocalcin 2/STC-2 Antibody [NBP1-92447] - Staining of human prostate shows strong cytoplasmic and membranous positivity in glandular cells.
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Applications for Stanniocalcin 2/STC-2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Stanniocalcin 2/STC-2

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

Alternate Names

STC-2, STC2, STCRP

Gene Symbol

STC2

Additional Stanniocalcin 2/STC-2 Products

Product Documents for Stanniocalcin 2/STC-2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Stanniocalcin 2/STC-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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