Stanniocalcin 2/STC-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-29193

Novus Biologicals, part of Bio-Techne
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NBP3-29193
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Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Stanniocalcin 2/STC-2 Antibodies »

Product Specifications

Immunogen

between 252 and 302

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Stanniocalcin 2/STC-2 Antibody

Stanniocalcin 2/STC-2 Antibody

Immunoprecipitation:Stanniocalcin 2/STC-2 AntibodyNBP3-29193] -

Immunoprecipitation:Stanniocalcin 2/STC-2 AntibodyNBP3-29193] -Detection of human Stanniocalcin 2 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-Stanniocalcin 2 antibody NBP3-29193 (lot NBP3-29193-2) used for IP at 6 µg per reaction. Stanniocalcin 2 was also immunoprecipitated by a previous lot of this antibody (lot NBP3-29193-1) and rabbit anti-Stanniocalcin 2 antibody BL5498 For blotting immunoprecipitated Stanniocalcin 2, NBP3-29193 was used at 0.4 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Applications for Stanniocalcin 2/STC-2 Antibody

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Stanniocalcin 2/STC-2

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

Alternate Names

STC-2, STC2, STCRP

Gene Symbol

STC2

Additional Stanniocalcin 2/STC-2 Products

Product Documents for Stanniocalcin 2/STC-2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Stanniocalcin 2/STC-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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