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Streptococcus pneumoniae Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-64502

Novus Biologicals, part of Bio-Techne
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NB100-64502
NB100-64502-0.25ml

Key Product Details

Species Reactivity

Bacteria

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

4.0 mg/ml

Product Specifications

Immunogen

Whole cell blend of numerous serotypes

Specificity

NB100-64502 recognizes Streptococcus pneumoniae and reacts with types 3, 4, 6, 7, 9, 14, 18, 19 and 23. S. pneumoniae is a non-motile gram-positive bacteria that is found in the human upper respiratory tract and often as diplococci (pairs of cocci). NB100-64502 is not absorbed and may react with related microorganisms.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Streptococcus pneumoniae Antibody

Immunohistochemistry: Streptococcus pneumoniae Antibody [NB100-64502]

Immunohistochemistry: Streptococcus pneumoniae Antibody [NB100-64502]

Immunohistochemistry: Streptococcus pneumoniae Antibody [NB100-64502] - Histopathology of lung sections collected at 24 hr pbi from mice co-infected with mouse adapted influenza A/Puerto Rico/8/34 (H1N1) (PR8) and type 2 pneumococcal strain D39 variants. Serial lung sections were subjected to immunohistochemistry (IHC) for pneumococcus using Rabbit Anti-Streptococcus pneumoniae Polyclonal Antibody (Catalog # NB100-64502) at 4 ug/mL or neutrophils using Rat Anti-Ly-6G6C Monoclonal Antibody (Catalog # NB600-1387) at 2 ug/mL. Representative images at 4x magnification with 60x magnification inset are shown. Images courtesy of Dr. Amanda P. Smith, UTHSC, TN //doi.org/10.1101/659557
Streptococcus pneumoniae Antibody

Immunohistochemistry: Streptococcus pneumoniae Antibody [NB100-64502] - 

Immunohistochemistry: Streptococcus pneumoniae Antibody [NB100-64502] - Effect of ethanol exposure on neutrophil and Streptococcus pneumoniae localization and bacterial phagocytosis after infection. IHC staining was performed on formalin-fixed lung sections with antibodies against Ly6G for neutrophils (brown) and S. pneumoniae (pink) and counterstained with hematoxylin. Representative images are at 100x magnification for the top panel (scale bar = 200um) and 400x magnification for the bottom panel (scale bar = 50 um). Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/35603143/) licensed under a CC-BY license.  
Streptococcus pneumoniae Antibody

Immunohistochemistry: Streptococcus pneumoniae Antibody [NB100-64502] -

Immunohistochemistry: Streptococcus pneumoniae Antibody [NB100-64502] - Effect of ethanol exposure on neutrophil & S. pneumoniae localization & bacterial phagocytosis after infection. (A) IHC staining was performed onformalin-fixed lung sections with antibodies against Ly6G for neutrophils (brown) & S. pneumoniae (pink) & counterstained with hematoxylin. Representative images are at 100x magnification for the top panel (scale bar = 200μm) & 400x magnification for the bottom panel (scale bar = 50 μm). (B) Percent phagocytosis of S. pneumoniae as measured by the ratio of cells with internalized bacteria to total nucleated cells. Black arrows denote cells with internalized S. pneumoniae. Data are presented as mean ± SEM. n = 3-4 mice per group per experiment & are representative of 2 individual experiments. *p < 0.05 by unpaired t test. Image collected & cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/35603143), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

4.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Streptococcus pneumoniae

Streptococci form part of the normal human flora that resides on the skin, and can also colonize the respiratory, gastrointestinal, and genitourinary tracts. Streptococci can cause a range of diseases, from the less serious but common sore throats and skin infections to life threatening conditions such as necrotising fasciitis. Different streptococcal species are involved in human disease, broadly categorized as pus forming or pyogenic streptococci, non pus forming or non pyogenic streptococci, and Streptococcus pneumoniae.

Alternate Names

Pneumococcal surface protein A, PSPA

Additional Streptococcus pneumoniae Products

Product Documents for Streptococcus pneumoniae Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Streptococcus pneumoniae Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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