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Synaptoporin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB300-738

Novus Biologicals, part of Bio-Techne
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NB300-738

Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. Accession # P22831

Reactivity Notes

It is anticipated that the antibody will work in mouse based on the fact that this species has 100% homology with the amino acid sequence used as antigen.

Localization

Integral membrane protein; Synaptic vesicles; Cytoplasmic vesicle; secretory vesicle; synaptic vesicle membrane.

Specificity

Specific for endogenous levels of the ~38 kDa Synaptoporin protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

38 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Synaptoporin Antibody

Western Blot: Synaptoporin Antibody [NB300-738]

Western Blot: Synaptoporin Antibody [NB300-738]

Western Blot: Synaptoporin Antibody [NB300-738] - Rat hippocampal lysate showing specific labeling of the ~38k Synaptoporin protein.

Applications for Synaptoporin Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:100

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Synaptoporin

Synaptophysin 2, also known as Synaptoporin, is a component of the synaptic vesicle membrane and thought to play an important role in synaptic vesicle trafficking (Dai et al., 2003). It is highly homologous to Synaptophysin 1, yet differs in expression. Whereas Synaptophysin 1 is ubiquitiously expressed, Synaptophysin 2 is concentrated in the mossy fiber synapses of the hippocampus (Grabs et al., 1994; Singec et al., 2002).

Alternate Names

DKFZp686G0883, MGC26651, SPO, synaptoporin

Entrez Gene IDs

72003 (Mouse); 66030 (Rat)

Gene Symbol

SYNPR

UniProt

Additional Synaptoporin Products

Product Documents for Synaptoporin Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Synaptoporin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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