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Synphilin-1 Antibody (2A8)

Novus Biologicals, part of Bio-Techne | Catalog # H00009627-M01

Novus Biologicals, part of Bio-Techne
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H00009627-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2A8

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

SNCAIP (NP_005451, 206 a.a. ~ 309 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PFCVLSPVKSPHLRKASAVIHDQHKLSTEETEISPPLVKCGSAYEPENQSKDFLNKTFSDPHGRKVEKTTPDCQLRAFHLQSSAAESKPEEQVSGLNRTSSQGP

Reactivity Notes

Human. Other species not tested.

Localization

Cytoplasmic

Specificity

SNCAIP - synuclein, alpha interacting protein (synphilin)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Synphilin-1 Antibody (2A8)

Sandwich ELISA: Synphilin-1 Antibody (2A8) [H00009627-M01] - Detection limit for recombinant GST tagged SNCAIP is approximately 0.03ng/ml as a capture antibody.

Applications for Synphilin-1 Antibody (2A8)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Synphilin-1

This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but their full-length nature has yet to be determined.

Alternate Names

Alpha-synuclein-interacting protein, MGC39814, Sph1, synphilin-1, synuclein, alpha interacting protein, SYPH1

Entrez Gene IDs

9627 (Human)

Gene Symbol

SNCAIP

OMIM

168 (Human)

Additional Synphilin-1 Products

Product Documents for Synphilin-1 Antibody (2A8)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Synphilin-1 Antibody (2A8)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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