TAK1 Antibody (3C9)

Novus Biologicals, part of Bio-Techne | Catalog # H00006885-M04

Novus Biologicals, part of Bio-Techne
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H00006885-M04
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 3C9

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TAK1 Antibodies »

Product Specifications

Immunogen

MAP3K7 (AAH17715.1, 471 a.a. ~ 579 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS

Specificity

Reacts with mitogen-activated protein kinase kinase kinase 7.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for TAK1 Antibody (3C9)

Western Blot: TAK1 Antibody (3C9) [H00006885-M04]

Western Blot: TAK1 Antibody (3C9) [H00006885-M04]

Western Blot: TAK1 Antibody (3C9) [H00006885-M04] - Analysis of MAP3K7 expression in transfected 293T cell line by MAP3K7 monoclonal antibody (M04), clone 3C9. Lane 1: MAP3K7 transfected lysatE (64.2 KDa). Lane 2: Non-transfected lysate.
ELISA: TAK1 Antibody (3C9) [H00006885-M04]

ELISA: TAK1 Antibody (3C9) [H00006885-M04]

ELISA: TAK1 Antibody (3C9) [H00006885-M04] - Detection limit for recombinant GST tagged MAP3K7 is 0.03 ng/ml as a capture antibody.

Applications for TAK1 Antibody (3C9)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against recombinant protein in WB and ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TAK1

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Long Name

TGF-beta activated kinase 1

Alternate Names

MAP3K7, TGF1a

Entrez Gene IDs

6885 (Human)

Gene Symbol

MAP3K7

UniProt

AAH17715 (Human)

Additional TAK1 Products

Product Documents for TAK1 Antibody (3C9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TAK1 Antibody (3C9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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