Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TAK1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a synthetic peptide corresponding to 14 amino acids near the amino-terminus of human TAK1 isoform a. The immunogen is located within amino acids 40 - 90 of TAK1. Amino Acid Squence: AIKQIESESERKAF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TAK1 Antibody - BSA Free

Western Blot: TAK1 AntibodyBSA Free [NBP1-76441]

Western Blot: TAK1 AntibodyBSA Free [NBP1-76441]

Western Blot: TAK1 Antibody [NBP1-76441] - Rat thymus cell lysate with TAK1 antibody at (A) 1, (B) 2, and (C) 4 ug/ml.

Immunocytochemistry/Immunofluorescence: TAK1 Antibody [NBP1-76441] -

Immunocytochemistry/Immunofluorescence: TAK1 Antibody [NBP1-76441] - Rat Thymus cells TAK1 antibody at 10 ug/mL.
TAK1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: TAK1 Antibody - BSA Free [NBP1-76441] -

Immunocytochemistry/ Immunofluorescence: TAK1 Antibody - BSA Free [NBP1-76441] - Immunofluorescence of TAK1 in Rat Thymus cells with TAK1 antibody at 10 u/mL.
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Applications for TAK1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Western Blot

1-4 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TAK1

TAK1 (TGF-beta activated protein kinase 1) is a widely expressed enzyme originally identified as a mitogen-activated protein kinase kinase kinase (MAP3K7). It has since been shown to mediate various intracellular signaling pathways, such as those induced by TGF-beta and members of the Toll-IL-1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. TAK1 is normally present in cells in a complex with TAK1-binding protein 1 (TAB1) and either TAB2 or TAB3. Association with TAB1 triggers TAK1 kinase activity by inducing TAK1 autophosphorylation, while TAB2 and possibly TAB3 may contribute to SAPK2a/p38a-mediated feedback inhibition of TAK1 activity.

Long Name

TGF-beta activated kinase 1

Alternate Names

MAP3K7, TGF1a

Gene Symbol

MAP3K7

UniProt

BAA25025 (Human)

Additional TAK1 Products

Product Documents for TAK1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TAK1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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