Key Product Details

Species Reactivity

Human, Monkey

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI4H5

Concentration

1 mg/ml

View all TAPBPR Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human TAPBPR (NP_060479) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TAPBPR Antibody (OTI4H5)

Western Blot: TAPBPR Antibody (OTI4H5) [NBP2-46066]

Western Blot: TAPBPR Antibody (OTI4H5) [NBP2-46066]

Western Blot: Tapasin Related Protein Antibody (OTI4H5) [NBP2-46066] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Tapasin Related Protein.
Immunohistochemistry: TAPBPR Antibody (OTI4H5) [NBP2-46066]

Immunohistochemistry: TAPBPR Antibody (OTI4H5) [NBP2-46066]

Immunohistochemistry: Tapasin Related Protein Antibody (OTI4H5) [NBP2-46066] - Analysis of Carcinoma of Human thyroid tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemistry: TAPBPR Antibody (OTI4H5) [NBP2-46066]

Immunohistochemistry: TAPBPR Antibody (OTI4H5) [NBP2-46066]

Immunohistochemistry: Tapasin Related Protein Antibody (OTI4H5) [NBP2-46066] - Analysis of Adenocarcinoma of Human colon tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Applications for TAPBPR Antibody (OTI4H5)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:150

Western Blot

1:200-2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TAPBPR

Tapasin Related Protein encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Long Name

Tapasin Related Protein

Alternate Names

Tapasin-like, TAPBPL, TAPBPR

Gene Symbol

TAPBPL

Additional TAPBPR Products

Product Documents for TAPBPR Antibody (OTI4H5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TAPBPR Antibody (OTI4H5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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