Tau Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18238

Novus Biologicals, part of Bio-Techne
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NBP3-18238
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Tau Antibodies »

Product Specifications

Immunogen

Recombinant Human Tau 2NR4 P301S Fibril

Localization

Cytoskeleton|Plasma Membrane|Cell Membrane|Peripheral MembraneProtein|Cytoplasmic Side|Cytosol|Axon|Microtubule|Microtubule Associated Complex|Tubulin Complex|Nucleus|Nuclear Periphery|NuclearSpeck|Axolemma Plasma Membrane|Axolemma|Cytoplasm|Cell Body|Cytoplasmic Ribonucleoprotein Granule|Dendrite|Growth Cone|Neurofibrillary Tangle|Neuronal Cell Body

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Tau Antibody - BSA Free

Western Blot: Tau Antibody [NBP3-18238]

Western Blot: Tau Antibody [NBP3-18238]

Western Blot: Tau Antibody [NBP3-18238] - Western blot analysis of SH-SY5Y showing detection of ~45.8 kDa Tau protein using Rabbit Anti-Tau Polyclonal Antibody (NBP3-18238). Lane 1: Molecular Weight Ladder (MW). Lane 2: SH-SY5Y. Load: 10 ug. Block: 5% Skim Milk powder in TBST. Primary Antibody: Rabbit Anti-Tau Polyclonal Antibody (NBP3-18238) at 1:1000 for 2 hours at RT with shaking. Secondary Antibody: Goat anti-rabbit IgG:HRP at 1:4000 for 1 hour at RT with shaking. Color Development: Chemiluminescent for HRP (Moss) for 5 min in RT. Predicted/Observed Size: ~45.8 kDa. Other Band(s): 50 kDa.
Immunohistochemistry: Tau Antibody [NBP3-18238]

Immunohistochemistry: Tau Antibody [NBP3-18238]

Immunohistochemistry: Tau Antibody [NBP3-18238] - Immunohistochemistry analysis using Rabbit Anti-Tau Polyclonal Antibody (NBP3-18238). Tissue: Brain Cortex. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-Tau Polyclonal Antibody (NBP3-18238).

Applications for Tau Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:1000
Application Notes
Optimal dilutions for assays should be determined by the user.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS pH 7.4, 50% glycerol

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Tau

Tau is a microtubule binding protein that promotes microtubule assembly and stability. Tau is found to be the major component of the paired helical filaments (PHFs) found in the brains of patients with Alzheimer disease (AD) (1,2). Tau is hyperphosphorylated in PHFs, and specific phosphorylation sites have been implicated in the loss of Tau's association with the membrane cortex during AD disease state, including Ser 199/202, Thr 231, and Ser 393/404 (3). Glycogen synthase kinase-3, or GSK-3, phosphorylates Tau on Ser 396 (4).

Long Name

Microtubule-Associated Protein Tau

Alternate Names

MAPT, MSTD, MTBT1, Neurofibrillary tangle protein, PPND

Gene Symbol

MAPT

Additional Tau Products

Product Documents for Tau Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Tau Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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