TBCC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85679

Novus Biologicals, part of Bio-Techne
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NBP1-85679
NBP1-85679-25ul
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Key Product Details

Validated by

Knockout/Knockdown, Independent Antibodies

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TBCC Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GLQKLINDSVFFLAAYDLRQGQEALARLQAALAERRRGLQPKKRFAFKTRGKDAASSTKVDAAPGIPPAVESIQDS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TBCC Antibody

Western Blot: TBCC Antibody [NBP1-85679]

Western Blot: TBCC Antibody [NBP1-85679]

Western Blot: TBCC Antibody [NBP1-85679] - Analysis using Anti-TBCC antibody NBP1-85679 (A) shows similar pattern to independent antibody NBP2-38233 (B).
Immunocytochemistry/ Immunofluorescence: TBCC Antibody [NBP1-85679]

Immunocytochemistry/ Immunofluorescence: TBCC Antibody [NBP1-85679]

Immunocytochemistry/Immunofluorescence: TBCC Antibody [NBP1-85679] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol.
Immunohistochemistry-Paraffin: TBCC Antibody [NBP1-85679]

Immunohistochemistry-Paraffin: TBCC Antibody [NBP1-85679]

Immunohistochemistry-Paraffin: TBCC Antibody [NBP1-85679] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.
View 1 more images

Applications for TBCC Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TBCC

Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

Alternate Names

CFCtubulin-specific chaperone c, tubulin folding cofactor C, Tubulin-folding cofactor C

Gene Symbol

TBCC

Additional TBCC Products

Product Documents for TBCC Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TBCC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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