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TC21/R-Ras2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32919

Novus Biologicals, part of Bio-Techne
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NBP1-32919

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Chicken (98%), Rat (100%), Zebrafish (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human TC21/R-Ras2. The exact sequence is proprietary.

Localization

Cell membrane, Lipid-anchor, Cytoplasmic side

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

23 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TC21/R-Ras2 Antibody

Western Blot: TC21/R-Ras2 Antibody [NBP1-32919]

Western Blot: TC21/R-Ras2 Antibody [NBP1-32919]

Western Blot: TC21/R-Ras2 Antibody [NBP1-32919] - Sample (30 ug of whole cell lysate) A: A431 12% SDS PAGE; antibody diluted at 1:5000.
Immunohistochemistry-Paraffin: TC21/R-Ras2 Antibody [NBP1-32919]

Immunohistochemistry-Paraffin: TC21/R-Ras2 Antibody [NBP1-32919]

Immunohistochemistry-Paraffin: TC21/R-Ras2 Antibody [NBP1-32919] - Paraffin-embedded DLD1 xenograft, using antibody at 1:500 dilution.
Western Blot: TC21/R-Ras2 Antibody [NBP1-32919]

Western Blot: TC21/R-Ras2 Antibody [NBP1-32919]

Western Blot: TC21/R-Ras2 Antibody [NBP1-32919] - Sample (50 ug of whole cell lysate) A: mouse brain 12% SDS PAGE; antibody diluted at 1:5000.

Applications for TC21/R-Ras2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:1000-1:10000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TC21/R-Ras2

RRAS2 (Related RAS viral oncogene homolog 2) is a member of the Ras superfamily. It is a GTP-binding protein with GTPase activity. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and is mutated in some human tumors and overexpressed in breast cancer cell lines.

Long Name

Teratocarcinoma Oncogene TC21

Alternate Names

RRAS2

Entrez Gene IDs

22800 (Human); 66922 (Mouse)

Gene Symbol

RRAS2

UniProt

Additional TC21/R-Ras2 Products

Product Documents for TC21/R-Ras2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TC21/R-Ras2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.