TCR alpha/beta Antibody (BMA031) [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-43550JF549

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Block/Neutralize, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Serum

Label

Janelia Fluor 549

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # BMA031

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TCR alpha/beta Antibodies »

Product Specifications

Immunogen

The original antibody was generated by immunizing mice with human perihperal blood T-lymphocytes.

Specificity

This antibody reacts with surface receptors on all alpha-beta TCR alpha/beta bearing cells, but does not react with receptors on gamma-delta T cells. TCR alpha/beta-alphabeta is expressed by the majority of mature CD3+ T cells.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for TCR alpha/beta Antibody (BMA031) [Janelia Fluor® 549]

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Serum

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TCR alpha/beta

The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.

Alternate Names

C), D, FLJ22602, J, MGC117436, MGC22624, MGC23964, MGC71411, T cell receptor alpha locus, T-cell antigen receptor, alpha polypeptide, T-cell receptor, alpha (V, TCRA, TCRD, TRA

Gene Symbol

TRA

Additional TCR alpha/beta Products

Product Documents for TCR alpha/beta Antibody (BMA031) [Janelia Fluor® 549]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TCR alpha/beta Antibody (BMA031) [Janelia Fluor® 549]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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