TfR (Transferrin R) Antibody (TFRC/1059)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-45007

Novus Biologicals, part of Bio-Techne
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NBP2-45007-0.1mg
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # TFRC/1059

Concentration

0.2 mg/ml

View all TfR (Transferrin R) Antibodies »

Product Specifications

Immunogen

Recombinant human TfR (Transferrin R) protein (Uniprot: P02786)

Localization

Cell surface

Specificity

It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This monoclonal antibody is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-11522)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for TfR (Transferrin R) Antibody (TFRC/1059)

Immunocytochemistry/ Immunofluorescence: TfR (Transferrin R) Antibody (TFRC/1059) [NBP2-45007]

Immunocytochemistry/ Immunofluorescence: TfR (Transferrin R) Antibody (TFRC/1059) [NBP2-45007]

Immunocytochemistry/Immunofluorescence: TfR (Transferrin R) Antibody (TFRC/1059) [NBP2-45007] - Immunofluorescence Analysis of Human K562 cells labeling CD71 with TfR (Transferrin R) Antibody (TFRC/1059) followed by Goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Red Dot (Red)
Flow Cytometry: TfR (Transferrin R) Antibody (TFRC/1059) [NBP2-45007]

Flow Cytometry: TfR (Transferrin R) Antibody (TFRC/1059) [NBP2-45007]

Flow Cytometry: TfR (Transferrin R) Antibody (TFRC/1059) [NBP2-45007] - Flow Cytometric Analysis of PFA-fixed K562 cells using TfR (Transferrin R) Antibody (TFRC/1059) followed by Goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).
Flow Cytometry: TfR (Transferrin R) Antibody (TFRC/1059) [NBP2-45007]

Flow Cytometry: TfR (Transferrin R) Antibody (TFRC/1059) [NBP2-45007]

Flow Cytometry: TfR (Transferrin R) Antibody (TFRC/1059) [NBP2-45007] - Human CD71 on Jurkat Cells. Black: Cells alone; Grey: Isotype Control; Green: AF488-labeled CD71 Monoclonal Antibody (TFRC/1059).

Applications for TfR (Transferrin R) Antibody (TFRC/1059)

Application
Recommended Usage

Flow Cytometry

1-2 ug/million cells

Immunocytochemistry/ Immunofluorescence

1-2 ug/ml
Application Notes
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: TfR (Transferrin R)

Useful in studies of dividing haematopoietic and tumour cell populations, and metabolic activity.

Long Name

Transferrin Receptor

Alternate Names

CD71, TfR (TransferrinR), TFR1, TFRC, TRFR

Gene Symbol

TFRC

UniProt

P02786 (Human)

Additional TfR (Transferrin R) Products

Product Documents for TfR (Transferrin R) Antibody (TFRC/1059)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TfR (Transferrin R) Antibody (TFRC/1059)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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