TGN46 Antibody (2F11)

Novus Biologicals, part of Bio-Techne | Catalog # H00010618-M02

Novus Biologicals, part of Bio-Techne
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H00010618-M02
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Key Product Details

Species Reactivity

Human, Monkey

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2F11

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TGN46 Antibodies »

Product Specifications

Immunogen

TGOLN2 (NP_006455, 229 a.a. ~ 327 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAE

Specificity

TOGLN2 (2F11)

Marker

TGN Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for TGN46 Antibody (2F11)

Immunocytochemistry/ Immunofluorescence: TGN46 Antibody (2F11) [H00010618-M02]

Immunocytochemistry/ Immunofluorescence: TGN46 Antibody (2F11) [H00010618-M02]

Immunocytochemistry/Immunofluorescence: TGN46 Antibody (2F11) [H00010618-M02] - Analysis of monoclonal antibody to TGOLN2 on HeLa cell . Antibody concentration 10 ug/ml.
Immunohistochemistry-Paraffin: TGN46 Antibody (2F11) [H00010618-M02]

Immunohistochemistry-Paraffin: TGN46 Antibody (2F11) [H00010618-M02]

Immunohistochemistry-Paraffin: TGN46 Antibody (2F11) [H00010618-M02] - Analysis of monoclonal antibody to TGOLN2 on formalin-fixed paraffin-embedded human small Intestine. Antibody concentration 3 ug/ml.
ELISA: TGN46 Antibody (2F11) [H00010618-M02]

ELISA: TGN46 Antibody (2F11) [H00010618-M02]

ELISA: TGN46 Antibody (2F11) [H00010618-M02] - Detection limit for recombinant GST tagged TGOLN2 is 0.03 ng/ml as a capture antibody.

Applications for TGN46 Antibody (2F11)

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TGN46

The trans-Golgi network (TGN) is part of the secretory pathway of eukaryotic cells which is distinct from the Golgi stack. The TGN is important in the later stages of protein secretion where it seems to play a key role in the sorting and targeting of secreted proteins to the correct destination. Some surface receptors recycle between the cell surface and the TGN, suggesting that the TGN is also important in endocytic pathways. TGN46 cycles between the trans-Golgi network and the cell surface returning via endosomes. It is thought to be involved in regulating membrane traffic to and from trans-Golgi network. Three splice isoforms are exist, TGN46, TGN48 and TGN51. Isoform TGN46 is the more widely expressed isoform. TGN48 is expressed in embryonic kidney and promyelocytic cells. Isoform TGN51 is abundant in fetal lung and kidney. TGN46 is a human specific protein. The rodent homologue of TGN46 is known as TGN38.

Alternate Names

TGN 46, TGN 48, TGN 51, TGN38, TGN-38, TGN38 homolog, TGN46, TGN-46, TGN48, TGN51, TGOLN 2, TGOLN2, trans golgi network 38, trans golgi network 46, Trans Golgi network integral membrane protein 2, Trans Golgi network integral membrane protein 2 [Precursor], Trans Golgi network protein (46 48 51kD isoforms), Trans golgi network protein 2, Trans Golgi network protein TGN51, Trans-Golgi network integral membrane protein 2, Trans-Golgi network protein 2, Trans-Golgi network protein TGN51, TTGN 2, TTGN2

Entrez Gene IDs

10618 (Human)

Gene Symbol

TGOLN2

OMIM

603062 (Human)

UniProt

NP_006455 (Human)

Additional TGN46 Products

Product Documents for TGN46 Antibody (2F11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TGN46 Antibody (2F11)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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