Thrombomodulin/BDCA-3 Antibody (SR1034) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22533

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22533-100ul
NBP3-22533-50ul
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Key Product Details

Species Reactivity

Mouse, Rat

Applications

Flow Cytometry, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1034

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Thrombomodulin/BDCA-3 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Thrombomodulin/BDCA-3 (Uniprot #: P15306)

Specificity

Detects endogenous levels of total Thrombomodulin/BDCA-3

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Thrombomodulin/BDCA-3 Antibody (SR1034) - BSA Free

Western Blot: Thrombomodulin/BDCA-3 Antibody (SR1034) [NBP3-22533] -

Western Blot: Thrombomodulin/BDCA-3 Antibody (SR1034) [NBP3-22533] - Western blot analysis using NBP3-22533 in mouse lung cell lysate.

Applications for Thrombomodulin/BDCA-3 Antibody (SR1034) - BSA Free

Application
Recommended Usage

Flow Cytometry

1:50

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thrombomodulin/BDCA-3

CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.

Alternate Names

BDCA-3, BDCA3, CD141, Fetomodulin, THBD, THRM

Gene Symbol

THBD

Additional Thrombomodulin/BDCA-3 Products

Product Documents for Thrombomodulin/BDCA-3 Antibody (SR1034) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Thrombomodulin/BDCA-3 Antibody (SR1034) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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