Thyroid Peroxidase Antibody (SR1031)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21923

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21923-100ul
NBP3-21923-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1031

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Thyroid Peroxidase Antibodies »

Product Summary for Thyroid Peroxidase Antibody (SR1031)

Immunogen

A synthesized peptide derived from human Thyroid Peroxidase (Uniprot #: P07202)

Specificity

Detects endogenous levels of total Thyroid Peroxidase

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

103 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Thyroid Peroxidase Antibody (SR1031)

Western Blot: Thyroid Peroxidase Antibody (SR1031) [NBP3-21923] -

Western Blot: Thyroid Peroxidase Antibody (SR1031) [NBP3-21923] - Western blot analysis using NBP3-21923 in Human thyroid lysate.

Applications for Thyroid Peroxidase Antibody (SR1031)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:40

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thyroid Peroxidase

Thyroid Peroxidase encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. [provided by RefSeq]

Alternate Names

EC 1.11.1, MSA, TDH2A, thyroid microsomal antigen, thyroid peroxidase, thyroperoxidase, TPXEC 1.11.1.8

Gene Symbol

TPO

Additional Thyroid Peroxidase Products

Product Documents for Thyroid Peroxidase Antibody (SR1031)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Thyroid Peroxidase Antibody (SR1031)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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