TIA1 Antibody (RM490)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18835

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-18835
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM490

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TIA1 Antibodies »

Product Summary for TIA1 Antibody (RM490)

Immunogen

A peptide corresponding to the C-terminus of human TIA1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TIA1 Antibody (RM490)

TIA1 Antibody (RM490)

Western Blot: TIA1 Antibody (RM490)[NBP3-18835]

Western Blot: TIA1 Antibody (RM490)[NBP3-18835]Western Blot of Jurkat cell lysate using anti-TIA1 rabbit monoclonal antibody (RM490) at 1:1000 dilution.

Applications for TIA1 Antibody (RM490)

Application
Recommended Usage

Western Blot

1:1000-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C.

Background: TIA1

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Alternate Names

cytotoxic granule-associated RNA-binding protein, nucleolysin TIA-1 isoform p40, p40-TIA-1, p40-TIA-1 (containing p15-TIA-1), RNA-binding protein TIA-1, T-cell-restricted intracellular antigen-1, TIA-1, TIA1 cytotoxic granule-associated RNA binding protein, TIA1 cytotoxic granule-associated RNA-binding protein

Gene Symbol

TIA1

Additional TIA1 Products

Product Documents for TIA1 Antibody (RM490)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TIA1 Antibody (RM490)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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