Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all TIAM1 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residues 1550 and the C-terminus (residue 1591) of human T-cell lymphoma invasion and metastasis 1 using the numbering given in entry NP_003244.1 (GeneID 7074)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TIAM1 Antibody

Western Blot: TIAM1 Antibody [NB100-2301]

Western Blot: TIAM1 Antibody [NB100-2301]

Western Blot: TIAM1 Antibody [NB100-2301] - Samples : Whole cell lysate from Mouse NIH3T3 (50 ug) and Jurkat (25 ug) cells. Antibody : Affinity purified rabbit anti-TIAM1 antibody used at 1 ug/ml. Detection : Chemiluminescence with an exposure time of 2 minutes.

Applications for TIAM1 Antibody

Application
Recommended Usage

Western Blot

1:1000-1:5000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: TIAM1

TIAM1 modulates the activity of RHO like proteins and connects extracellular signals to cytoskeletal activities. It acts as a GDP dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO like GTPases and activates them. It activates RAC1, CDC42, and to a lesser extent RHOA.

Long Name

T-cell Lymphoma Invasion and Metastasis 1

Alternate Names

FLJ36302, human T-lymphoma invasion and metastasis inducing TIAM1 protein, 10TIAM-1, T-cell lymphoma invasion and metastasis 1, T-lymphoma invasion and metastasis-inducing protein 1

Entrez Gene IDs

7074 (Human); 21844 (Mouse)

Gene Symbol

TIAM1

UniProt

NP_003244.1 (Human)

Additional TIAM1 Products

Product Documents for TIAM1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TIAM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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