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TLK2 Antibody (2G7)

Novus Biologicals, part of Bio-Techne | Catalog # H00011011-M01

Novus Biologicals, part of Bio-Techne
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H00011011-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2G7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

TLK2 (AAH44925, 1 a.a. ~ 126 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQRNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQP

Reactivity Notes

Human. Other species not tested.

Localization

Nuclear

Specificity

TLK2 - tousled-like kinase 2

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for TLK2 Antibody (2G7)

Western Blot: TLK2 Antibody (2G7) [H00011011-M01]

Western Blot: TLK2 Antibody (2G7) [H00011011-M01]

Western Blot: TLK2 Antibody (2G7) [H00011011-M01] - TLK2 expression in Hela NE ( Cat # L013V3 ).
Immunocytochemistry/ Immunofluorescence: TLK2 Antibody (2G7) [H00011011-M01]

Immunocytochemistry/ Immunofluorescence: TLK2 Antibody (2G7) [H00011011-M01]

Immunocytochemistry/Immunofluorescence: TLK2 Antibody (2G7) [H00011011-M01] - Analysis of monoclonal antibody to TLK2 on HeLa cell. Antibody concentration 10 ug/ml.
Immunohistochemistry-Paraffin: TLK2 Antibody (2G7) [H00011011-M01]

Immunohistochemistry-Paraffin: TLK2 Antibody (2G7) [H00011011-M01]

Immunohistochemistry-Paraffin: TLK2 Antibody (2G7) [H00011011-M01] - Analysis of monoclonal antibody to TLK2 on formalin-fixed paraffin-embedded human colon tissue. Antibody concentration 5 ug/ml.

Applications for TLK2 Antibody (2G7)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunofluoresence, immunohistochemistry (paraffin), and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TLK2

TLK2 (Tousled-like kinase 2) is a nuclear serine/threonine kinase. It is cell cycle checkpoint and ATM-pathway dependent, with maximal activity in S-phase. It is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. TLK2 is potentially involved in the regulation of chromatin assembly during DNA replication.

Alternate Names

EC 2.7.11, EC 2.7.11.1, MGC44450, PKU-ALPHA, serine/threonine-protein kinase tousled-like 2, tousled-like kinase 2serine/threonine kinase

Entrez Gene IDs

11011 (Human)

Gene Symbol

TLK2

OMIM

608439 (Human)

Additional TLK2 Products

Product Documents for TLK2 Antibody (2G7)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TLK2 Antibody (2G7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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