Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI2D10

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TLK2 Antibodies »

Product Specifications

Immunogen

Recombinant protein fragment corresponding to amino acids 1-296 of human TLK2 (NP_006843) produced in E.coli.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for TLK2 Antibody (OTI2D10) [DyLight 405]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TLK2

TLK2 (Tousled-like kinase 2) is a nuclear serine/threonine kinase. It is cell cycle checkpoint and ATM-pathway dependent, with maximal activity in S-phase. It is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. TLK2 is potentially involved in the regulation of chromatin assembly during DNA replication.

Alternate Names

EC 2.7.11, EC 2.7.11.1, MGC44450, PKU-ALPHA, serine/threonine-protein kinase tousled-like 2, tousled-like kinase 2serine/threonine kinase

Gene Symbol

TLK2

Additional TLK2 Products

Product Documents for TLK2 Antibody (OTI2D10) [DyLight 405]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TLK2 Antibody (OTI2D10) [DyLight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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