TLR5 Antibody (8-1#)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41489

Novus Biologicals, part of Bio-Techne
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NBP3-41489
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Key Product Details

Species Reactivity

Human, Rat

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 8-1#

Concentration

1 mg/ml

View all TLR5 Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human TLR5 (Uniprot#: O60602; Tyr693-Ser858 (Uniprot#: O60602)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for TLR5 Antibody (8-1#)

TLR5 Antibody (8-1#)

Immunohistochemistry-Paraffin: TLR5 Antibody (8-1#) [NBP3-41489] -

Immunohistochemistry-Paraffin: TLR5 Antibody (8-1#) [NBP3-41489] - DAB staining on IHC-P; Sample: Rat Lymph node Tissue; Primary Ab: 20ug/ml NBP3-41489; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
TLR5 Antibody (8-1#)

Western Blot: TLR5 Antibody (8-1#) [NBP3-41489] -

Western Blot: TLR5 Antibody (8-1#) [NBP3-41489] - Sample: Recombinant TLR5, Human.
TLR5 Antibody (8-1#)

Western Blot: TLR5 Antibody (8-1#) [NBP3-41489] -

Western Blot: TLR5 Antibody (8-1#) [NBP3-41489] - Sample: Rat Spleen lysate Primary Ab: 0.6ug/ml NBP3-41489; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

Applications for TLR5 Antibody (8-1#)

Application
Recommended Usage

Immunohistochemistry

5-50ug/mL

Western Blot

0.5-5ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TLR5

The Toll like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin 1 receptor-associated kinase (IRAK) signaling pathway. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens.

Long Name

Toll-like Receptor 5

Alternate Names

TIL-3

Gene Symbol

TLR5

Additional TLR5 Products

Product Documents for TLR5 Antibody (8-1#)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TLR5 Antibody (8-1#)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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