TLR6 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76664

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TLR6 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to 13 amino acids near the center of human TLR6. The immunogen is located within amino acids 390 - 440 of TLR6. Amino Acid Squence: SWNSLESGRHKEN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TLR6 Antibody - BSA Free

Western Blot: TLR6 AntibodyBSA Free [NBP1-76664]

Western Blot: TLR6 AntibodyBSA Free [NBP1-76664]

Western Blot: TLR6 Antibody [NBP1-76664] - Jurkat cell lysate with TLR6 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.

Immunocytochemistry/Immunofluorescence: TLR6 Antibody [NBP1-76664] -

Immunocytochemistry/Immunofluorescence: TLR6 Antibody [NBP1-76664] - Jurkat cells with TLR6 antibody at 2 ug/ml.

Applications for TLR6 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

2 ug/ml

Western Blot

0.5-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TLR6

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify. Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan. Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses.

Long Name

Toll-like Receptor 6

Alternate Names

CD286

Gene Symbol

TLR6

UniProt

NP_006059 (Human)

Additional TLR6 Products

Product Documents for TLR6 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TLR6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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