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TMEM119 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-30551

Novus Biologicals, part of Bio-Techne
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NBP2-30551-25ul
NBP2-30551

Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human, Rat, Porcine, Feline

Cited:

Human, Rat

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ITRQKQKASAYYPSSFPKKKYVDQSDRAGGPRAFSEVPDRAPDSRPEEALD

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Feline, Porcine reactivity reported from verified customer reviews.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TMEM119 Antibody

Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551]

Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551]

Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551] - Staining in human lymph node and liver tissues. Corresponding TMEM119 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551]

Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551]

Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551] - Staining of human cerebral cortex, liver, lymph node and testis using Anti-TMEM119 antibody NBP2-30551 (A) shows similar protein distribution across tissues to independent antibody NBP2-30792 (B).
Immunocytochemistry/ Immunofluorescence: TMEM119 Antibody [NBP2-30551]

Immunocytochemistry/ Immunofluorescence: TMEM119 Antibody [NBP2-30551]

Immunocytochemistry/Immunofluorescence: TMEM119 Antibody [NBP2-30551] - Human microglia cell line stained with TMEM antibody and DAPI. ICC/IF image submitted by a verified customer review.

Applications for TMEM119 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Verified from a customer review. Reported in scientific literature (PMID: 29109020).

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Frozen

Verified from a customer review.

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reviewed Applications

Read 5 reviews rated 2.6 using NBP2-30551 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2), 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMEM119

ATF4 is an approximately 38 kDa member of the bzip family of transcription factors. It plays an important role autophagy, the unfolded protein response, and the response to oxygen and nutrient deprivation. These functions are regulated by the dimerization of ATF4 with the leucine zipper protein FIAT. ATF4 contains a basic DNA-binding domain (aa 280-300) and a leucine zipper domain (aa 306-334).

Long Name

Transmembrane Protein 119

Alternate Names

OBIF

Gene Symbol

TMEM119

UniProt

Additional TMEM119 Products

Product Documents for TMEM119 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TMEM119 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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