TMEM59 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76497

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Mouse (94%), Porcine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TMEM59 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near amino terminus of human TMEM59. The immunogen is located within amino acids 80 - 130 of TMEM59. Amino Acid Squence: ECESACTEAYSQSDEQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TMEM59 Antibody - BSA Free

Western Blot: TMEM59 AntibodyBSA Free [NBP1-76497]

Western Blot: TMEM59 AntibodyBSA Free [NBP1-76497]

Western Blot: TMEM59 Antibody [NBP1-76497] - Human kidney tissue lysate with TMEM59 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: TMEM59 Antibody - BSA Free [NBP1-76497]

Immunocytochemistry/ Immunofluorescence: TMEM59 Antibody - BSA Free [NBP1-76497]

Immunocytochemistry/Immunofluorescence: TMEM59 Antibody [NBP1-76497] - Immunofluorescence of TMEM59 in human kidney tissue with TMEM59 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: TMEM59 Antibody - BSA Free [NBP1-76497]

Immunohistochemistry-Paraffin: TMEM59 Antibody - BSA Free [NBP1-76497]

Immunohistochemistry-Paraffin: TMEM59 Antibody [NBP1-76497] - Human kidney tissue with TMEM59 antibody at 2.5 ug/mL.

Applications for TMEM59 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMEM59

Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.

Long Name

Transmembrane Protein 59

Alternate Names

C1orf8, DCF1, HSPC001, PRO195, UNQ169

Gene Symbol

TMEM59

UniProt

NP_004863

Additional TMEM59 Products

Product Documents for TMEM59 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TMEM59 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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