TNF RI/TNFRSF1A Antibody (H398) [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37724CL1

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP2-37724AF350

Alexa Fluor 405

NBP2-37724AF405

Alexa Fluor 488

NBP2-37724AF488

Alexa Fluor 532

NBP2-37724AF532

Alexa Fluor 594

NBP2-37724AF594

Alexa Fluor 647

NBP2-37724AF647

Alexa Fluor 700

NBP2-37724AF700

Alexa Fluor 750

NBP2-37724AF750

Allophycocyanin

NBP2-37724APC

Allophycocyanin/Cy7

NBP2-37724APCCY7

Biotin

NBP2-37724B

DyLight 350

NBP2-37724UV

DyLight 405

NBP2-37724V

DyLight 488

NBP2-37724G

DyLight 550

NBP2-37724R

DyLight 594

NBP2-37724DL594

DyLight 650

NBP2-37724C

DyLight 680

NBP2-37724FR

DyLight 755

NBP2-37724IR

FITC

NBP2-37724F

HRP

NBP2-37724H

Janelia Fluor 525

NBP2-37724JF525

Janelia Fluor 549

NBP2-37724JF549

Janelia Fluor 585

NBP2-37724JF585

Janelia Fluor 635

NBP2-37724JF635

Janelia Fluor 646

NBP2-37724JF646

Janelia Fluor 669

NBP2-37724JF669

mFluor Violet 450 SE

NBP2-37724MFV450

mFluor Violet 500 SE

NBP2-37724MFV500

mFluor Violet 610 SE

NBP2-37724MFV610

PE

NBP2-37724PE

PE/Atto594

NBP2-37724PEATT594

PE/Cy5.5

NBP2-37724PECY55

PE/Cy7

NBP2-37724PECY7

PerCP

NBP2-37724PCP

Forumulation

Catalog #

Azide and BSA Free

NBP2-37724

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Block/Neutralize, CyTOF-ready, Flow Cytometry, Functional, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG_2A Clone # H398

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TNF RI/TNFRSF1A Antibodies »

Product Specifications

Immunogen

Recombinant full length human CD120a.

Specificity

Antibody recognizes the extracellular domain of CD120a, a 55 kDa receptor for tumor necrosis factor. Antibody blocks biological activity of both natural and recombinant human TNF alpha and TNF beta.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for TNF RI/TNFRSF1A Antibody (H398) [CoraFluor™ 1]

Application

Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: TNF RI/TNFRSF1A

The protein encoded by the TNF Receptor I gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. (provided by RefSeq)

Long Name

Tumor Necrosis Factor Receptor I

Alternate Names

CD120a, TNFRI, TNFRSF1A

Gene Symbol

TNFRSF1A

Additional TNF RI/TNFRSF1A Products

Product Documents for TNF RI/TNFRSF1A Antibody (H398) [CoraFluor™ 1]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for TNF RI/TNFRSF1A Antibody (H398) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
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