TNF RI/TNFRSF1A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88140

Novus Biologicals, part of Bio-Techne
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NBP1-88140
NBP1-88140-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TNF RI/TNFRSF1A Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECVSC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TNF RI/TNFRSF1A Antibody

Western Blot: TNF RI/TNFRSF1A Antibody [NBP1-88140]

Western Blot: TNF RI/TNFRSF1A Antibody [NBP1-88140]

Western Blot: TNF RI/TNFRSF1A Antibody [NBP1-88140] - Analysis in human cell line CAPAN-2.
Immunohistochemistry-Paraffin: TNF RI/TNFRSF1A Antibody [NBP1-88140]

Immunohistochemistry-Paraffin: TNF RI/TNFRSF1A Antibody [NBP1-88140]

Immunohistochemistry-Paraffin: TNF RI/TNFRSF1A Antibody [NBP1-88140] - Staining of human gallbladder shows moderate cytoplasmic positivity in glandular cells.
Western Blot: TNF RI/TNFRSF1A Antibody [NBP1-88140]

Western Blot: TNF RI/TNFRSF1A Antibody [NBP1-88140]

Western Blot: TNF RI/TNFRSF1A Antibody [NBP1-88140] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

Applications for TNF RI/TNFRSF1A Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TNF RI/TNFRSF1A

The protein encoded by the TNF Receptor I gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. (provided by RefSeq)

Long Name

Tumor Necrosis Factor Receptor I

Alternate Names

CD120a, TNFRI, TNFRSF1A

Gene Symbol

TNFRSF1A

Additional TNF RI/TNFRSF1A Products

Product Documents for TNF RI/TNFRSF1A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TNF RI/TNFRSF1A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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